Reproducibility

• Eliminate process variability
• Remove potential for human error
• Achieve traceable, repeatable and scalable protein sample preparation
• Enable consistent sample preparation across triplicate wells with a CV of less than 2% and a standard curve linearity (R2) of over 99% during serial dilution in proteomic workflow analytical assays

Throughput

• Achieve maximum throughput without the need for additional headcount
• Experience a hassle-free installation process with support to run your preferred protocols
• Get quick and consistent results with standardized workflows
• Unleash the full potential of our automated liquid handling solutions with their large deck capacity, use of on-deck devices, and the selective tip feature of the multichannel head offering flexibility for both low- and high-throughput applications

Scalable and Modular

• Seamlessly enhance your workflow with direct integrations of plate readers, incubators, positive pressure ALP, BioShake and ColdPlate
• Effortlessly transfer reagents for LC-MS prep with our Liquid Span-8 pipette and fixed tips

Biomek Automated Workstations

Automated tip-based liquid handling

• Ideal for medium- to high-throughput workflows
• Microliter-to-milliliter transfers with high precision and speed
• Complete walkaway solution that is flexible and versatile allowing a variety of sample sizes, reagent volumes, labware, device integrations and supplemental steps to transform your workflows
• Biomek i-Series workstations can run the ELISA assay including the wash steps on a deck with a CV <5%
• Automating quantitative methods, such as the Bradford assay, on the Biomek i-Series instruments provides consistent quality results as the scale increases for total protein quantification; the results yielded were an R-squared of 0.991 with CV < 2%
• Automated sample preparation on a Biomek i7 reliably streamlines proteomic analysis for diverse samples, overcoming biomarker discovery hurdles
• Automated Biomek Workstations when combined with Valita Titer assay and Molecular Devices SpectraMax iD5 Multi-Mode Microplate reader provides a high-throughput, fully automated and reproducible solution for accurate IgG quantification throughout drug development and manufacturing; this workflow demonstrates the quantification of up to 456 samples (5 x 96-well plates) in little over an hour, with the presentation of a direct output of IgG titer results
• Use of magnetic bead-based technology in combination with automated Biomek workstations allows for fast and efficient sample preparation for CE-LIF based N-glycosylation analysis of therapeutic antibodies; this innovative workflow enables glycoprotein sample preparation in under 4 hours, eliminating the need for centrifugation or vacuum centrifugation steps

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Echo Acoustic Liquid Handlers

Automated tip-less and contact-free liquid handling

• Enables assay miniaturization through precise nanoliter-scale transfers
• The Echo liquid handler enables protein crystal formation with sitting drop volumes as small as 50 nL; miniaturization reduces protein and reagent consumption in crystallization trials
• Dynamic Fluid Analysis allows transfer of proteins and essentially all sparse matrix screens using a single fluid class setting, which eliminates the need for multiple settings or frequent calibrations
• Transfer of samples from any well of a source to any destination further minimizes sample consumption and simplifies proteomic assay setup and execution
• Reduces dependency on single-use plastic pipette tips, which helps minimize carbon footprint
• Echo-enabled CFPE (Cell-Free Protein Expression) improves efficiency for expression screening, labeling, NMR, crystallization, mutagenesis, and screening enzymes

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Access Solutions Group

Transform your liquid handlers into advanced proteomics workflow solutions by seamlessly integrating the devices you need; our experts have integrated 300+ different third-party devices from over 60 manufacturers.

Our state-of-the-art multi-device robotic systems are specifically engineered to enhance your lab's throughput, accuracy and scalability.

From simple to complex workflows, optimize your data quality and user experience with the integration of single-purpose devices (or workflow steps) including:

Barcode readers • Microplate centrifuges • Plate readers and imagers • Plate transport devices • Plate washers • Positive Pressure ALPs • Capillary Electrophoresis • Sonication • Safety and biocontainment enclosures • Temperature-controlled storage • Tube handling/capping/decapping devices • Vacuum • Homogenization • Microplate Washing • Reagent dispensing • Sample weighing

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View Automated Liquid Handling Software

Get reliable results without the need to learn automation language. Simplify the complexity of sample and data handling through our software package add-ons to meet your proteomics workflow needs.

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Use pipette tips from Beckman Coulter Life Sciences for quality you can rely on.

Available in volume capacities from 0.5 μL to a full 1 mL, our pipette tips are certified to be free* from DNase/RNase/Protease, DNA (human and mouse), PCR inhibition, pyrogen, endotoxins, and trace-metals, and are made only from 100% premium-grade virgin polypropylene.

*below detectable levels

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