Connecting Scientific Discovery and Laboratory Automaton Innovation - SLAS Tutorial #2

Translating Nature into Medicine Using Machine Learning, Metabolomics, and High-Throughput Pharmacology Tutorial

Tuesday, February 8, 2022
Save the Date
11:30 am–12:30 pm ET
Room 107, Meeting Level 1

ABOUT

At Enveda, we are building the largest integrated dataset of plant chemistry in the world, tailor-made for drug discovery. With metabolomics analyses of thousands of plants linked to a knowledge graph (BIOEDGE) integrating humanity’s collective knowledge about plants and our internal high-throughput bioassay data, we are uniquely positioned to scale the discovery of first-in-class small molecules for complex human diseases.

Identifying and isolating active compounds from plants has historically been a slow, iterative and labor-intensive process. While our algorithms are quickly identifying active features and chemical structures from plants, our bioactivity assays must scale at a similar pace. Over the past few months we have scaled our bioactivity assays by an order of magnitude by leveraging the Echo 655, while simultaneously improving assay quality. Rapidly miniaturizing our assays to 1536-well plates and leveraging the Echo has allowed us to screen our growing library across numerous assays within a few months. With every experiment, our dataset grows, and our platform improves.

We continuously learn something about both our unique library and disease biology that we reintroduce into our dataset to fine-tune our algorithms. We are grateful to partner with Beckman Coulter Life Sciences to explore the millions of phytochemicals that exist in nature to rapidly identify active molecules to treat human disease. 

A complimentary lunch will be served.

YOUR HOST

Jordan Toutounchian, Ph.D.

Director of Bioassays, Enveda Biosciences

Read Bio

Biomek Automated Workstations and Biomek NGeniuS Next Generation Library Prep Systems are not intended or validated for use in the diagnosis of disease or other conditions. In development. Performance characteristics have not been validated.

© 2022 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein, including Biomek and Biomek NGeniuS, are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. All other trademarks are the property of their respective owners.

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